Wednesday, April 24, 2019

Ohanaeze Youths Canvass For Igbo House Of Reps Speaker


BY CHRIS OJI, OTABOR OSAGIE

ENUGU (THE NATION)
-- The youth wing of the apex Igbo socio-cultural organisation, Ohanaeze Ndigbo, has cautioned the ruling All Progressives Congress (APC) against side-lining the Igbo in the sharing of principal offices of the National Assembly.

Ohanaeze Youths said: “It is a big insult and an affront to the Igbo nation that the Southeast is not in the consideration of APC for any key principal position in the Ninth National Assembly leadership.”

The group spoke through its Deputy National Youth Leader, Dr. Kingsley Dozie.

It frowned at the non-inclusion of the Southeast on the list of zones to produce the presiding officers for the Ninth National Assembly.

Ohanaeze Youths said it was aware that the APC leadership, backed by the Presidency, had endorsed Senator Ahmed Lawan (Northeast) for Senate President and Femi Gbajabiamila (Southwest) for the Speaker House of Representatives.

It added: “We query the justification in zoning the presiding officers of the National Assembly to regions that already have a fair share.

“We contend that since the President and Vice-President came from the North and the Southwest, justice and equity demand that either the Senate President or Speaker of the House of Representatives should come from the Southeast.

“Since APC has already zoned the Senate Presidency to the Northeast and the Deputy to the Southsouth, the Southeast should be allowed to produce the Speaker of the House of Representatives.

“If they say we have no ranking senator from their party, will they also say we don’t have qualified APC members in the House of Representatives, where one of them is returned for the fourth term in the name of Mrs Onyejeocha?

“Nigeria stands on the tripod of Igbo, Hausa and Yoruba, hence the distribution of political offices should reflect this equilibrium without excluding any tribe.

“APC’s orchestrated plans to exclude the Southeast from the Nigerian Project and power bloc will be resisted and any attempt to relegate Ndigbo to the background would not succeed.

“The Ndigbo are not visitors in Nigeria and not second class in the Nigerian Project. We cannot be treated as such. We are not slaves and can never be. Nigeria belongs to us all and this is a fact everybody must learn to live with.


“We urge members of the National Assembly to cede the Speakership position to the South East to foster unity and National cohesion.”

Also, the member representing Estako Federal Constituency in Edo State, Johnson Oghuma, has said the next Speaker of the House of Representatives will come from the South.

Oghuma, who was re-elected on the platform of the All Progressives Congress (APC), said there was no need exchanging fireworks with the main opposition Peoples Democratic Party (PDP) since the ruling party has the numbers to produce the Speaker.

The lawmaker addressed reporters in Auchi after distributing empowerment items to 800 residents of his constituency.

He said the Eighth National Assembly dominated by the PDP was an obstacle to the Executive, thereby frustrating developmental plans of President Muhammadu Buhari’s administration.

Oghuma said the incoming Ninth National Assembly will ensure harmonious relationship between the Executive and the Legislature to fast-track good governance for the Nigerians.

He said: “Nigerian should expect things to be different this time round. You know it is not too long that I went to the House. I was voted into the National Assembly in February 17, 2017. I discovered that members of my party at the Senate and the House of Representatives were problems to the APC-led government at the centre.

“The Ninth Assembly will collaborate with the Executive. Our role is complementary. No one is an island. We are supposed to work together to give the desire results that Nigerians are yearning for. Our people are suffering.

“President Buhari meant so well for our people; he is not stealing our money. He believes that the people should have what they are entitled to. That is why we will support him and the Judiciary to succeed.”

He said beneficiaries have received training in fishery, tailoring, welding, solar power repairs and installation, cosmetology, CCTV installation and repairs, as well as aluminium fabrication.

Biafra Can’t Be Achieved Through Agitation – Ezeonwuka



BY DAVID ONWUCHEKWA

NNEWI (SUN NEWS)
-- A member of the Board of Trustees of the All Progressives Grand Alliance (APGA), Chief Rommy Ezeonwuka, has said Biafra can’t be achieved through mere agitation but investment in Igbo land.

Ezeonwuka said it is a misnomer for Igbo to keep asking for an independent state of Biafra, but go ahead to develop other cities outside Igboland “when such investments outside would have been enough to give the Igbo political and economic independence without agitation.”

He lamented what he described as Igbo’s lack of think-home philosophy as they continued to build mansions and factories in diaspora without recourse to invest in their homeland, asking for Biafra at the same time.

The APGA chieftain said it would not be an overstatement to say Igbo are the most enterprising race in black Africa but have not been able to harness their potentialities to their best advantage.

“Nobody should give Ndigbo Biafra. We already have Biafra here with us and Biafra belongs to us; as was declared on May 30, 1967.

“It is an act of stupidity to ask anybody to give you Biafra. The land of Biafra is crying because our people in Diaspora have abandoned it to develop other areas like Abuja, Lagos and other places and you are here telling them to give you Biafra,” he said.

Ezeonwuka, who is the proprietor of Rogenny Games Village, Oba, and a big-time investor in sports and entertainment industry insisted that things could be produced in Biafran land, labeled made in Biafra and exported to other countries of the world with general acceptability.

On herdsmen’s killings in some parts of the country, Ezeonwuka said the Federal Government should ban open grazing without wasting further time.

From Zaria To Osogbo, The Making Of Curatorial Marvel – Part 1

‘A Man & Two Wives II – A Revisit of The Sunshine Period’, Bruce Onobrakpeya, 1960-70 via The Guardian
BY GREGORY AUSTIN NWAKUNOR

In 1959, Nigerian College of Arts, Science and Technology, Zaria, awarded Diploma in Fine Arts to its first graduate. Sixty years after, GREGORY AUSTIN NWAKUNOR (Arts and Culture Editor) looks at the place of Zaria Art School in Modern Nigeria’s Art history.

Art, in Nigeria, no doubt, is experiencing an explosion. Once restricted to ‘underfunded departments’ on university and polytechnic campuses and ‘overly dedicated starving artists’, it has gradually staked a claim for the country’s millennial culture. The development of Modern Nigerian Art could be linked to colonial influence, especially techniques and forms taught by Western expatriates /missionaries. However, in his Modern Nigerian Art: A Discursive Sketch, Prof. C. Krydz Ikwuemesi insists that the West did not introduce art to Nigeria. His words: “Europe did not teach art to Africa… In pre-colonial Nigeria, there were many kinds of artistic expressions ranging from painting and carving to textile design.”

Ikwuemesi adds, “although some Western scholars will classify them as traditional (in one of its pejorative senses), I insist, in the words of John Picton, that where such arts exist (as in the case of the uli painting tradition of the Igbo of eastern Nigeria), they are contemporary arts that, while drawing upon a continuity with the past as the basis of (their) existence, (are) about the here and now, addressing local concerns within a sense of local modernity.”

Hannah O’Leary, Sotheby’s Head of Modern and Contemporary African Art, attests to the growing influence of Modern Nigerian Art. She says, “we are seeing a monumental shift in the art market towards greater diversity and a surge in interest in contemporary art from Africa, and of course, Nigeria is leading the way. Our African auctions see bidding from every corner of the globe, and we are proud to promote the very best Nigerian art to an international audience.”

Recognising the growing influence of Nigerian, by extension, African arts, Sotheby’s — the world’s oldest and largest auction house — had its inaugural sale of Modern and Contemporary African Art in May 2017. The second edition, in 2018, attracted 62 artists from 16 African countries and buyers from 33 different countries. A third of successful bidders were notably from Africa.

The auction house also experienced a renewed popularity among collectors, as 19 per cent of these buyers were new to Sotheby’s. Estimated at a total of £1,167,500-£1,707,000 ($1,654, 698-$2,419,331), the sale was led by two Nigerian artists — the pioneer of African modernism Ben Enwonwu, whose work Africa Dances was sold for £187,500 ($265,744), six times more than the estimated £20,000- £30,000; and À La Warhol by Njideka Akunyili Crosby, a self-portrait inspired by the silk screen portraits of Andy Warhol, which fetched £200,000 ($283,460), doubling its estimate of £50,000- £70,000. Akunyili Crosby, incidentally, is one of the two Nigerians listed in this year’s Venice Biennale holding from May 11 to November 24, 2019.

Another auction house, Bonhams, has also discovered the explosive interest in Modern and Contemporary Nigerian Art. The long-lost masterpiece sold for £1.2 million ($1.67 million) at Africa Now, the first-ever evening sale of Contemporary African art at Bonhams London. The painting had been assumed lost for decades before the family that owned it invited a Bonhams specialist to appraise it late in 2017. Tutu was last publicly exhibited in 1975 at the Italian embassy in Lagos. Enwonwu made three original Tutu works featuring Princess Adetutu Ademiluyi, of which this is the second. The first of three Tutu paintings done in 1973 was stolen in 1994 and its whereabouts remain unknown.

Only on March 20, 2019, Nigeria’s Enwonwu also made a strong showing at the modern and contemporary African art sale by Bonhams.
His Anyanwu, 92 x 21 x 14cm (36 1/4 x 8 1/4 x 5 1/2in), led Bonhams’ sale. It sold for £187,563 (estimate £100,000-150,000).Anyanwu is one of the artist’s most accomplished and recognisable works.

Aina Onabolu, Kenneth Murray and the coming of art education

THE credit for development of Modern Nigerian art is traced to Aina Onabolu (1882–1963), who by teaching himself to draw without any formal art education, proved Africans were capable of producing academic and naturalistic paintings, contrary to general misconceptions at the time. Onabolu was to later study art in England, the first African person to do so.He introduced Western art to Africa without any European assistance. He singlehandedly introduced formal art education to Nigerian schools and laid the foundation for a younger generation of artists to build on.

In 1926, Onabolu requested an art teacher to assist with his art teaching programme in Lagos schools, and in 1927, the colonial education department sent Kenneth Murray (1902–1972) from England. Murray would take Onabolu’s dream of formal art education to the Western and Eastern regions.However, where Onabolu called for a complete break with the traditional arts of Nigeria and production of a modern subject through the new medium of academic easel painting, Murray argued for a return to the glories of traditional art against the onslaught of modernity and artistic modernism.

Be that as it may, through a combination of Onabolu’s perception and training, coupled with those of Kenneth Murray’s — an expatriate art teacher who encouraged indigenous expression of art forms and styles — and many others who organised formal and informal workshops at that time, a rounded curriculum was inadvertently achieved in Nigeria, spawning the genius of Nigeria’s first Modern Art master, Odinigwe Benedict Chukwukadibia Enwonwu.

Enwonwu is arguably the most influential African artist of the 20th century. His pioneering career opened the way for the postcolonial proliferation and increased visibility of Modern African Art. He was one of the first African artists to win critical acclaim, having exhibited in august show spaces in Europe and the United States and listed in international directories of contemporary art.However, few artists experience the honour of having one of their works become a national cultural icon. Enwonwu’s portraits of Tutu achieved this level of celebrity. During his time, Enwonwu was well regarded and his art described as a “unique form of African modernism.”Professor Sylvester Ogbechie describes his art as “[the opening up of] third space in art history whose nature and parameters are at variance with art history’s exclusionary narratives of modernity and its inscription of the modern artist-subject as a white, Western European male.”Ogbechie says, “as an African modern artist, he used his practice to develop a new kind of modern art whose ideals of representation and notions of artistic identity were different from conventional art-historical narrative of European modernist practice.”

According to Ikwuemesi, Onabolu and Enwonwu merely set the stage for the ensuing creative departure that was to occur at the Nigerian College of Arts, Science and Technology (NCAST), now Ahmadu Bello University, Zaria, between 1958 and 1961 through the efforts of some young art students, namely Uche Okeke, Solomon Irein Wangboje, Bruce Onobrakpeya, Simon Olaosebikan, Oseloka Osadebe, Felix Ekeada, Ogbonnaya Nwagbara, Yusuf Grillo, Emmanuel Odita, Simon Okeke, Demas Nwoko and Ikpomwosa Omagie, the only female among them. They were not all classmates except for the fact that their duration of training in Zaria overlapped.

Starting from 1958, under the aegis of the organisation, which they had formed, the Zaria Arts Society, these students began to agitate for a change in the curriculum of the arts programme from its essentially Eurocentric aesthetic position to integrate African aesthetic praxis as part of its offering. Nicknamed the ‘Zaria rebels’ by Ghanaian-born art historian, Kojo Fosu, the society was a conscious movement fuelled by the first generation graduates of the college (1958 – 1961). This group later went on to influence every sphere of visual arts in Nigeria.

But Timothy Adebanjo Fasuyi is sometimes credited as the main proponent of the movement, being the first graduate of the institution (Painting, 1959). His fame, in fact, grew when Clara Etso Ugbodaga-Ngu, the first Nigerian teacher on the staff of NCAST, who taught drawing, asked him to speak on traditional Nigerian art. Ikwuemesi said, “their stylistic stance critically influenced the course of art in Nigeria and helped to give character to Nigerian modernism in the post-independence era.”

The making of Modern Nigerian Art 

CRITICS have argued that with Onabolu, Murray, Enwonwu and the Zaria Arts Society, Nigerian art stopped being traditional tribal masks and carvings, raffia and woven crafts — today’s artists are well read, well travelled and tackling contemporary issues such as, oil spillage, immigration, war, famine and femininity. Strange and wonderful in numerous ways, Nigerian art scene sheds new light on both the performance as well as plastic aspects of visual art while reminding everybody that eccentricity is not only basic to creativity but also to personal liberty and democracy itself.From a sprawling cacophony of objects, photographs and films to videos, installations, sculptures, drawings and prints, sometimes even, sometimes uneven, haphazard selection, Nigeria has been orchestrated into a curatorial marvel.Their unusually optimistic-sounding titles inadvertently have raised large and intriguing interests.

How Zaria influenced Mbari Club, Osogbo Art School

BUT soon, the convergence that illuminated their instincts and gave currency to their work happened: the Mbari movement at Ibadan. At about this time, active in their prime — all born in the 1930s — Chinua Achebe had moved from Enugu in 1961 to assume duties as the Director of External Broadcasting of Nigerian Broadcasting Service (NBS) in Lagos, Christopher Okigbo moved from the Library of the University of Nigeria, Nsukka, as the pioneer acting University Librarian to become the West African Regional Manager of the Cambridge University Press in Ibadan, Wole Soyinka had returned from the UK and was a Rockefeller Research Fellow in the University of Ibadan, and had also founded his theatre company, the Orisun Theatre Company; J.P. Clark was an Information Officer in the Western Region’s Ministry of Information in Ibadan, and Ulli Beier was traveling back and forth between Ibadan, Osogbo and Ede for the University of Ibadan Extra Mural Studies, and editing the new journal, the Black Orpheus. Nwoko was active on return from Paris in the Ibadan Theatre, where he was engaged to design stages for theatre productions, and was equally busy creating the famous U.I. Wall murals; Onabrakpeya nearby in Lagos came often, and Uche Okeke was at the Enugu end of the Mbari club, on Uwani Street. The effect was a cultural synergy that gave impetus to a new artistic impulse in Nigeria.

The essential nucleus of the Mbari movement was around these individual writers and artists, who indirectly influenced the birth of Osogbo Art School. The Osogbo art workshop experiment originated from a series of creativity-development exercises in Ibadan, Ede and Osogbo. And it originated serendipitously from Ulli Beier’s prompting and encouragement to the late Duro Ladipo to convert his popular recreation centre and bar located on the ground floor of his house to the Mbari Club house.

The first group of students that participated in the Mbari workshop (Ibadan) conducted by Beier comprised the late Jacob Afolabi, the late Rufus Ogundele, Chief Muraina Oyelami, Yinka Adeyemi, Ademola Onibokuta, Adebisi Fabunmi, the late Tijani Mayakiri Jire and Alake Buraimoh (nee Ajibola).On the second run of the workshop that was conducted by Georgina Beier in Osogbo in 1964, over 30 participants attended – comprising Duro Ladipo Theatre Company members and others.

At the end of that exercise, four major artists: Chief Taiwo Olaniyi (aka Twins Seven Seven), Oyelami, Adebisi Fabunmi and Jimoh Buraimoh emerged from the lot – all of whom later became internationally renowned studio artists. Incidentally, none of them had gone to a college before attending the workshop, neither were they previously involved in the arts.

According to Jimoh Buraimoh, “Zaria, in those days, used to be known for photographic art, but the students always found it difficult to find their footing when they left school, because they were not trained to be original. When Osogbo Art School started turning out students, critics were insulting them, calling them all manner of names, deriding them as people with no university education and others. But despite this, we were excelling.”

Buraimoh told The Guardian, “Osogbo arts gave birth to Ife arts and impacted greatly on Nsukka arts. Osogbo arts made all the institution in the country to have an area of specialisation. Nsukka arts was known for wall decorations and other related artforms, but after seeing how Osogbo had metamorphosed it turned its type of arts into contemporary arts. Ife that believed in olokun (river goddess) also did the same. They were all influenced by Osogbo arts, which was good for the country, because it made each school to have an identity of the type of art they want.”

Art masters on recess

TODAY, these artists are considered Modern Nigerian Art masters — the pacesetters, so to say.
But who is a master? How good must a painter be to qualify as a Master?Critics have argued that becoming a master artist is not about finishing; in fact, art is never really finished, something will always come and follow, something will be what is next, and there you will find yourself as an artist trying to grow and learn again. Mastery is about continuing to learn even in the longest of time and efforts.

In 2007, during a group show titled, Living Masters, at Terra Kulture, Victoria Island, Lagos, the questions of who is a master and when will an artist attain the mastery of art came up. Mrs. Sinmidele Adesanya, the owner of Mydrim Gallery, had argued that mastery of art “takes a lifetime of practice and perfecting as well as having influence in the form of mentoring and teaching.”
She noted that whatever gains Nigerian visual arts profession has recorded, in expansion and art appreciation, they cannot be divorced from the past efforts of the modern and contemporary masters. “Young artists today need to know the history of those who paved the way for them.”

In the second show titled, the Masters (2018), Mrs, Adesanya insisted that the contribution of the masters to the development of Nigerian art is worth more attention. “All of the masters in this exhibition have dedicated their lives to serving the art and have extensively studied, researched and honed their talent. These artists have the clout that is not born in a day. Mydrim would like to draw more attention than to the names of these artists, because their skill and creativity presuppose and speak for themselves. Not only that but they also create emblems of Nigerian society at large and add depths to the culture.

The art critic, Terry Hollis, in his comprehensive elaboration of what is expected of master artists, The Characteristics of a Master Artist, highlighted the following as essential: Resilience, originality, accountability, love for art and eccentricity.He says, “many master artists are resilient because they know that every mistake in their artwork creates room for perfection. They work on their mistakes and take criticism positively. They do a lot of research in their work, which enables them to realise their mistakes. Some also carry out several experiments that inspire them to come up with good art pieces.”He adds, “master artists have a unique feature in their art works that distinguish them from other pieces. Master artists use varying techniques such as brush strokes, geometrical shapes, abstract objects or silhouettes to do all their art pieces.”

Master artists can account for every detail in their art pieces. They know why they place every detail in their art piece. They do not depend on the set rules of doing art pieces to enable art readers to understand their work. Hollis said, “a master artist dedicates his entire life to art. He treats art as a profession and everything he does is related to it. This love for art is what gives him the zeal to make unique pieces. His passion for art is evident in every aspect of his life.”

Creativity, in general, is marked by the combination of rational and irrational thoughts, and turning this into art requires artists to go deeper and deeper into the unknown to create. SIXTY years after producing first Zaria Art School graduate graduate, how much of these attributes can be seen in these master artists:

TA Fasuyi

THOUGH an artist, Fasuyi had a long career in education sector, where he was also an administrator. He spent the last six years of his career at the Federal Ministry of Education to improve Federal Government Colleges nationwide. As an educationist, Fasuyi ensured that art endured as every Federal Government School had, at least, one art teacher.For five years, Fasuyi, also known as Tafas, and a native of Isona, Osun State, served as Federal Art Adviser. He retired from the Ministry of Education on his 50th birthday. He has since then been a full-time studio artist till date.From figural to landscape and abstraction, Fasuyi’s paintings radiate the energy of an artist who was privileged to be part of history, especially in the context of evolving Nigerian modernity, over the five decades of his practice.In simplified figure painting style that lures the uninitiated into the perception that creating an art piece is not as difficult, Fasuyi, in this body of work, brings his mid-career styles into the contemporary period of his later years, suggesting that the art and the artist cannot afford to remain only in the past glory.

Bruce Obomeyoma Onobrakpeya 

ONOBRAKPEYA is considered one of the most successful artists to have emerged in Africa during the 20th century.The fusion of his training in Western techniques and materials blended into his background, culture and ingenuity that is irrefutably indigenous, yet exotic. His rich textured works are a blend of native folklores, faith, environmental reflections and supernatural essences.
Since 1966, as an experimental artist, Onobrakpeya has discovered, innovated and perfected several techniques both in printmaking and relief sculpture that are uniquely Nigerian. At the same time, he began to experiment with forms in relation to Nigerian folklore, myths and legends. Much of his work uses stylistic elements and compositions derived from traditional African sculpture and decorative arts.

Prof. Sunny Awhefeada, who teaches literature at the Delta State University, Abraka, says, “Bruce Onobrakpeya is a living art avatar, who shares the same hallowed platform with Picasso, Leonardo da Vinci and Michael Angelo in the universal configuration of artistic influence!” Awhefeada says, “much of the motif of Onobrakpeya’s art is rooted in his Urhobo tradition as he gives visual representation to ethno-philosophy, folklore, politics, environment, religion, modernity… While Urhobo tradition provides his collage, the world remains his canvas.”Onobrakpeya created the Bruce Onobrakpeya Foundation, of which he is President, and which organises the yearly Harmattan workshop in his hometown of Agbara Otor, Delta State.

The foundation is an artist-led non-governmental organisation formed in 1999. It aims to encourage the growth of art and culture by giving artists opportunities to gain skills, while increasing public awareness of African art and its benefits to society.
It is a forum to inspire and help support visual artists. This initiative aids to develop the potential of Nigerian artists through the provision of opportunities by means of skills acquisition, training and mentoring.

An exhibition of new installation works by Bruce Onobrakpeya titled, ‘Beauty and The Machine’, will hold from April 20 to May 10, 2019 at the Freedom Park, Lagos. It is the first of a series of shows to commemorate 60 years of the artist’s public presentation of his art through exhibitions.

According to Kennii Ekundayo, curator of the show, “‘Beauty And The Machine’ will feature — never been exhibited — line of works that make a bold statement on the value still present in materials that have been discarded, and deemed unusable. It is a presentation of artworks achieved from abandoned items, all of which have now been recycled and assembled to become components of artistic productions.”

She added, “this installation art style is no stranger to the several techniques innovated and improvised upon in the age-long practice of Onobrakpeya. It is a style borne out of his childhood fascination of the workings of machines, which outcome-wise, he has successfully made a part of his artistic expressions. The exhibits are made up of car parts, fabric materials, metals, beads, wood, computer parts, iron rods, steel, aluminum, and plastic parts, with interesting designs and spaces that have been realisable for the artist to reshape to create captivating art forms.”

She said, “‘Beauty And The Machine’ through its exhibits, aims to lend voice to the clamour on the importance of recycling as a means of environmental sanitation as the incorporation of these erstwhile worthless materials into embodying art, not only improves upon the aesthetics of our environment but is beneficial to the revenue growth of our economy and most importantly, a propagation of the art.”

Uche Okeke

OKEKE was at the forefront of this artistic movement. Much of his work is grounded in Igbo folklore and mythology, depicting spirits and masqueraders. The fluid, broad brushstrokes of his compositions owe to the linear uli designs of the Igbo people. Okeke tenure as departmental head in University of Nigeria, Nsukka, which he joined in 1970, aided this style, consequently propagating this distinctive school and art form through his students and colleagues. His inspirations were profoundly Igbo artistic forms; systems which he came to absorb after his art education, and the experimental phase of his earlier work.

The Nsukka Uli culture or the Nsukka School of art is not Okeke’s alone; it is a result of the agglomerate success of all working within and beyond this style. As Uche Okeke claims, “it was the predisposition, the consequence of the Nigerian-Biafran Civil War, and the productivity of some of the post-war generation of the art faculty (and the students as well) that truly brought Igbo cultural base to the Nsukka Art Department.”

In his lecture titled, ‘Uche Okeke: An Enduring Embodiment of Art Revolution’, Prof. Ola Oloidi, described him as an unrepentant apostle of art revolution. As an apostle of art decolonisation, Okeke was influenced by the nationalistic revolution that was targeted against the colonial powers through his art. According to him, he was the first to make poetry an integral part of visual art. He was also one of the most important promoters of critical writing in Nigeria and made drawing a full profession in UNN. Okeke died on January 5, 2016, following a long struggle with a devastating stroke, at his home in Nimo, in the Njikoka area of Anambra State, where he had established the Asele institute on his retirement from academics.

Yusuf Grillo

GRILLO is considered one of the country’s outstanding and academically trained painters. He came to prominence and international recognition in the 1960s and 1970s, while exhibiting a large collection of his early works.Known for his inventive works and the prominence of blue in many of his paintings, Grillo makes use of his western art training in many of his paintings, combining western art techniques with traditional Yoruba sculpture characteristics. His preference for blue in natural settings paintings is sometimes similar to the adire or resist-dye textiles used in Nigeria.

Those who are familiar with his work may know that Grillo has expressed an aversion to photo-realism; rather than aiming for lifelike creations, he instead prefers to elongate and stylise the figures. This technique, which produces graceful, elegant human-like forms, makes his work instantly recognisable. His choice of colour tones and his compositional decisions have been praised by many, including Kunle Filani, a well-known art critic. Filani noted that whilst many have attempted to mimic Grillo’s style in their own work, none has managed to achieve the same skilful combination of complimentary hues and perfect spatial balance.

Unlike his stained glass and mural work, Grillo’s paintings were rarely the result of commissions. In an interview in 2005, the artist revealed that painting was his preferred medium and the majority of his works were executed for his own enjoyment. Consequently, the themes and concepts are his, and not subject to “market requirements”.Grillo sources his inspiration from the actions and behaviour of humankind, but is particularly intrigued by Yoruba culture, and much of his artwork tends to merge western and Yoruba art techniques.Music making, a recurring motif in Grillo’s work, is inspired by where he was raised —the Brazilian Quarters in Lagos, an area renowned for the quality of its live bands. These childhood experiences would inspire some of the artist’s works including, ‘Drummer and Apprentice’, ‘Quartet’, ‘Trio’ and ‘Drummer’s Return’. At 85, Grillo still works in the studio after his retirement from Yaba College of Technology where he created the famous Yaba Art School.

Demas N. Nwoko 

Nwoko, born in 1935, in Delta State, has designed several private and public buildings. In addition to impressive terra-cotta works, and numerous mural paintings, Nwoko’s stage and costume designs of the FESTAC production of ‘The Children Of Paradise’ will continue to be some of the best ever. Demas studied stage design in Paris, in 1963, under a scholarship from the Congress of Cultural Freedom.

Nwoko sees design as an ingenuous activity that carries with it a focus on social responsibility for positive influences in the environment and culture of the society. Nwoko has been operating a syncretism in between multiple architectural languages, combining Igbo Nigerian architecture, and Japanese construction techniques, since the 1970s. Some of Nwoko’s famous architectural works include, the Dominican mission in Ibadan, Oyo State; the Oba Akenzua Theatre in Benin City and the Cultural Centre in Ibadan. He also has a magnificent private edifice called ‘New Culture Studios’ in Ibadan.Three architectural innovations are attributed to him: re-interpretation of the traditional Igbo court, the double skinned exterior wall and the use of stabilised and pressed earth blocks. New Culture Studio was his first architectural construction. It consists of a residence and production space with an adjacent theater.

The building was built with local resources: brick, laterite and granite. Evoking Greek architecture, each entrance presents a covered gallery held up by a colonnade while the theatre, a prototype, still under construction, is presented as a semicircular shape at the opening of the zenith. The decorative aspects are expressed by blending patterns from Igbo and Beninese cultures, molded and sculpted in polychrome materials. It was the architect’s first endeavour into researching and developing acoustics, the importance given to water, the modulation of natural light and to the skin of the building.

The success of Amos Tutuola’s Palmwine Drinkard owes a little bit of credit to the effort of Nwoko. His inventive creations helped organise the choreography and direction of the play and brought to life the themes of Tutuola in every act of the play. His body of stage design and direction, which started at Ibadan, includes, Wole Soyinka’s A Dance of the Forests, Bertholt Brecht’s Der Kaukasische Kreidekreis (The Caucasian Chalk Circle), and the Mbari Theatre production of John Pepper Clark’s ‘The Masquerade’.

Jimoh Akolo 

Jimoh Akolo was born in Egbe, Kogi State, Nigeria in 1935. He graduated from NCAS, Zaria, in 1961, alongside many of the members of the Zaria Art Society. He also imbibed the tenets of synthesising modern art forms with the indigenous concepts.Naturalistic in orientation, he combines traditional African proportions in his forms to create a unique blend. Mr. Dennis Dueden at Keffi Government College where he was educated from 1950 to 1956 spotted Jimoh’s talent. He specialised in painting. Akolo did not exactly oppose the Zaria artists’ much talked about ‘rebellion’ against the art forms of their colonial era teachers. But he was said to have taken his own kind of ‘natural synthesis’ home, leaning towards Yoruba native form.

“He wanted to be more broad in his expression,” Mrs Adesanya described Akolo’s different artistic route. Between 1961 and 1962, he studied in London and exhibited at the Commonwealth Institute, Whitechapel Art Gallery and many other places. He later studied audiovisual art in Indiana University between 1964 and 1965.A prolific painter with exceptional sculptural techniques, Jimoh’s mural adorns the Northern House of Assembly (the Lugard Hall), Kaduna. He has also exhibited in Brazil and the United States of America. He retired as a Professor at the Ahmadu Bello University where he served in various administrative capacities before retirement.

Simon Obiekezie Okeke 

The late Simon will remain one of the most devoted, hardworking and gifted artists. His untimely death has robbed the art world of an exceptional master painter and sculptor.Another product of Zaria Art School (1956 – 1960) specialising in sculpture mainly because at that stage he felt that he could continue with painting confidently on his own.He joined the Nigerian Museums from where he went abroad between 1961 and 1962 to study museum technique at the laboratories of the British Museum. He rose to the post of Curator of National Museum, Onikan, Lagos in 1966. He died during the Nigerian Civil War.

Scientists Validate More Herbs For Hair Growth



BY CHUKWUMA MUANYA, STANLEY AKPUNONU & ADAKU ONYENUCHEYA

THE GUARDIAN

Scientists have validated the use of local herbs including sandal wood, onions, garlic, guava, shea butter, Aloe vera, neem oil, olive oil, black seed, rice water, tomato, pawpaw and coconut oil for hair loss, dandruff, baldness and premature graying of hair.

The use of shea butter, pawpaw (Carica papaya) and polysaccharide mixture to enhance hair growth and hair restoration for damaged hair has received a United States (US) patent: US 20050053564 A1.

The abstract noted: “The present invention includes methods for the treatment and/or prevention of hair loss and methods for the regeneration or restoration of hair growth comprising a step of identifying an individual suffering from or susceptible to hair loss or hair thinning or in need of hair regeneration, and a step of administering of a plant extract identified as Shea butter in combination with papaya and polysaccharides. Preferably, the extract is an aqueous extract and is administered topically.

“The present invention also provides a composition, preferably in the from of a lotion, gel, cream, or other suspension, and a distinct chemical compound or class of chemical compounds therein, effective in restoring hair growth, preventing hair loss, and/or reversing the effects of hair thinning. The composition may include an effective amount of a hair loss preventative or hair growth promoting composition comprising a plant extract identified as Shea Butter in combination with papaya and polysaccharides.”

Commonly called Shea butter in Nigeria, okwuma in Igbo and ori in Yoruba, Butyrospermum parkii/Vitellaria paradoxa, is a tree of Sapotaceae family, indigenous to Africa. The Shea fruit consists of a thin, tart, nutritious pulp, surrounding a relatively large, oil-rich seed, from which Shea butter is extracted. Shea butter is a fat obtained from the fruit of the tree. It is commonly used in hair and skin care products due to its properties as an excellent skin conditioner. It is believed to promote hair growth and is considered especially beneficial to processed, damaged and heat-treated hair.

The benefits of Shea butter can be attributed to the concentration of vitamins A, E and F, along with cinnamic esters, sterols, minerals and other nutrients. Vitamin F is made up of linoleic acid and alpha-linoleic acid. These fatty acids are believed to soothe, hydrate, balance and revitalize both the hair and the scalp.

Papaya is the fruit from the plant pawpaw (Carica papaya). It is mostly found in tropical countries like Nigeria, India, Sri Lanka, Jamaica, Indonesia, Brazil and Vietnam. Along with other benefits papaya is said to be great for hair. It helps hair by: maintaining the natural shine of the hair; keeping the hair soft; stimulating hair growth; restricting the dandruff; relaxing the hair; and making the hair fuller and stronger by firming it.

Papaya is rich in proteins, vitamin B6, vitamin C, iron, magnesium, beta-carotene among others.

Another study published in International Journal of Pharmacy Research and Development (IJPRD) has found that onions have proven additional hair-restoring capabilities. The study concluded: “Onions contain a number of important minerals and vitamins, such as vitamins C and B6, calcium, magnesium, potassium, and germanium. Onion also has high sulphur content. Sulphur is a mineral present in every cell in our body, with its greatest concentration in hair, skin and nails. It has often been called the “beauty mineral” and the “healing mineral” because of its ability to promote circulation and decrease inflammation. These qualities also lend to the theory that adequate amounts of sulphur can jump-start hair growth in people with deficiencies.High amounts of sulphur in onions make them particularly effective in regenerating hair follicles and stimulating hair regrowth. In addition, naturally-concentrated sulphur compounds have been proven to show additional hair-restoring.”

Scientists have also successfully treated hair loss with Allium sativum (garlic). The researchers in a study published in Kufa Medical Journal concluded: “Garlic is an efficient and rapid topical treatment for alopecia areata. It is cheep, available and with negligible side effects.”

Alopecia areata is a non-scarring localized hair fall, probably of autoimmune ateology, that responds to treatment with many topically applied irritant substances.
Aloe vera has long been known as one of nature’s miracle plants, being used to cure everything from minor skin irritations to burns. But today, it is being touted as nature’s hair growth aid, able to help those suffering with thinning hair, alopecia, and even dandruff achieves impressive results. Aloe vera gel is good for promoting hair growth, moisturizing the hair, and eliminating bacteria that can be caused by excessive oil build up and dandruff on the scalp. Aloe vera gel contains an enzyme that helps to increase blood circulation in the scalp, which helps prevent hair loss and helps rejuvenate hair follicles for increased hair growth in both men and women.

If used at the onset of thinning hair and alopecia, the regular use of Aloe vera gel has been known to reduce or even cure some cases of baldness.

Another study published in Journal of Pharmacy Research has demonstrated the therapeutic potential of Psidium guajava (guava) and its polyherbal formulation on chemotherapy induced baldness (alopecia).

Specifically, the young leaves of the guava are rich in a myriad of vitamins, minerals and flavonoids. It has been studied and documented for its many health benefits, exemplifying its bioactive properties as, but not limited to, an antioxidant, antimicrobial, anti-cough, and anti-inflammatory. It has been used to alleviate illness and ailments including but not limited to those related to cardiovascular, intestinal, allergies, diabetes and pain mediator.

Olive oil can actually slow down the body’s natural production of DHT when it is applied to the scalp, so it provides a minor decrease in the hair loss caused by male pattern baldness.

One of the main benefits of olive oil for hair growth is that it strengthens hair follicles and shafts, preventing hairs from breaking off quickly. The fatty acids of olive oil make an ideal conditioner for hair, and when hair is properly conditioned, in bends under pressure instead of breaking and snapping off.

Neem can also be used for hair related problems. Azadirachta Indica (neem) and other parts of the neem are useful to prevent dandruff, hair loss and to prevent grey hair. The neem-based cream can be applied on the scalp before going for bathing to treat dandruff. Various shampoo and other products made of neem are also available in the market to prevent dandruff, hair loss and to keep hair healthy. It can also be used to prevent scalp related problems which keeps scalp healthy. Neem oil is mixed with almond oil and coconut oil to keep the hair healthy.

A study published in the Journal of Medicinal Plants Studies evaluated hair oil formulations used for hair loss disorder. The researchers noted: “Hair plays a vital role in the personality of human and for their cure we use lots of cosmetic products. The fading (pigmentation problem), dandruff, alopecia (loss of hair) is the major problem associated with hairs. Ayurvedic system is the traditional system of medicine having major treatment across globe. The aim of study is to develop a hair oil formulation using Azadirachta indica/neem tree (leaves), Semecarpus anacardium (fruits), Trigonella foenum graecum (seeds), Cocos nucifera/coconut (oil) for better growth of hair and diminution in loss of hair (alopecia).”

Meanwhile, millions of men who are going bald may benefit from rubbing sandalwood oil onto their scalps. Laboratory tests of scalp tissue by German researchers found it stimulates hair growth after just six days. Bizarrely, hair follicles are thought to contain ‘smell receptors’ that respond to the aromatic odour and trigger the main protein in hair to multiply.

Although humans and animals are only able to smell through their noses, receptors in hair, sperm and even our guts are able to recognise chemicals in certain aromas. The findings could lead to a sandalwood-based balding treatment that may benefit the quarter of men who start to lose their hair by the time they turn 25.

Studies have already shown that exposing human skin cells to sandalwood in the lab causes the protein keratin to multiply, which speeds up wound healing.

Intrigued whether the aromatic wood may also boost hair growth, the researchers from the Monasterium Laboratory, Münster, exposed human scalp tissue to the artificial sandalwood-like odour Sandalore.

Sandalore is often added to fragrances and moisturisers to give a sandalwood aroma, and has previously been used in previous experiments investigating its effect on keratin. The scalp tissue came from donors, who were aged between 38 and 69 years old, who had recently undergone face-lift surgery. Six days after the tissue was exposed to Sandalore, its keratin levels began to increase.

This is thought to be due to the oil blocking the genes that cause keratin cells to ‘commit suicide’ in a process known as apoptosis. Results, published in the journal Nature Communications, also suggests the aromatic oil stimulates the release of ‘growth factors’.

These can include vitamins or hormones that are necessary for cells to multiply and thrive. Sandalore is thought to promote hair growth by acting on the smell receptor OR2AT4, which is present in hair follicles. When the scalp tissue was exposed to both Sandalore and the rose-like odour Phenirat, hair growth stopped. Phenirat is a known OR2AT4 blocker.

The researchers believe this demonstrates Sandalore stimulates hair growth by acting on OR2AT4. They add this could help them develop a balding treatment for humans. Although it may seem odd that scent receptors are present in hair follicles, such receptors are actually ancient chemical signalling systems that evolved before humans developed a sense of smell.

Also, cannabidiol or CBD is a very popular natural remedy used for different purposes. Hair loss is currently one of the major problems for some people all across the world. The CBD hair oil is also an exceptional natural hair growth product, which is prepared from the marijuana or hemp plant.

Tetrahydrocannabinol or THC is the major cannabinoid founded in the mixture of products of the Cannabidiol. Products of Cannabidiol can be used to fix pain related issues and symptoms without affecting the other parts of the body.

One of the main ingredients in traditional beard oil and a major component of beard balm is Cannabis Sativa Seed Oil (also known as Hemp Oil).

Hemp Seed oil penetrates and is absorbed easily into the skin, helping to replenish oils missing due to sun exposure and poor nutrition. It is full of vitamins containing vitamins A, C, E, proteins, Beta-carotenes, as well as being rich in essential omega-3, 6 and 9 fatty acids, along with nutrients that make it perfect for all hair types as well as giving benefits for skin. Although loved by many, its familiar nutty scent can take a little getting used to for some people.
hemp oil for hair

Hemp oil has high moisturizing properties which nourishes not just the beard and facial hair, but also the skin and scalp. Being high in Vitamin E makes it a great natural hair conditioner.

Hemp oil penetrates into the skin and hair easily and is an excellent source of Omega 6 which is also known as GLA (Gamma linolenic acid), a vital ingredient for hair growth, it both stimulates growth and nourishes hair, assisting in keratin production which gives thicker, stronger, and healthier hair.

Beaten Candidate Of Dublin-Based Association For Igbo People Takes Challenge To The High Court

Ireland's Four Courts in Dublin, location of Supreme Court, High Court and Central Criminal Court. Image: Independent

BY AODHAN O'FAOLAIN, RAY MANAGH

CASTLEKNOCK, DUBLIN (THE JOURNAL) -- The unsuccessful candidate for the position of President of a Dublin-based association that represents the Igbo people has launched High Court proceedings aimed at preventing the victor from being sworn in.

The application has been brought by Emmanuel Ejezie, from Castleknock, Dublin against the Igbo Union Dublin (IUD) which is an organisation made up of people from the South East of Nigeria known as the igbo or Ndi Igbo.

He claims the elections for the union’s position of President and Vice President that took place last July were flawed due to the spread of bizarre election conspiracies and actions by certain members of the IUD to ensure their preferred candidates were elected.

He seeks orders preventing the successful candidate Mr Arinze Onwuka from being sworn in as the IUD’s new president, which is due to take place in the coming days.

The court heard Mr Onwuka won the election by 109 votes to Mr Ejezie’s 104 votes.

Today Mr Ejezie’s barrister Venetia Taylor Bl for told the court there were “serious irregularities” during the election, conducted on 15 July last, which rendered the election “a sham.”

Counsel said these included the IUD’s refusal to allow some 18 persons who were entitled to vote in the election enter the hall where ballots were being cast.

Counsel said on the night of the election those persons preventing from voting waited outside the hall for over six hours in heavy rain.

Other persons, counsel said, turned up and were allowed to vote at a time after when voting was supposed to finish.

In a sworn statement Mr Emmanuel Ejezie described the IUD’s election as being “not out of place in Putin’s Russia or some other totalitarian system.”

Mr Ejezie, who described himself as “a small public service vehicle operator” living in Ireland for over a decade, said that he was looking forward to being president as it would have been the greatest honour of his life, and “a dream come true”.

What occurred he said has led to “disenfranchisement, discrimination and inhuman and degrading treatment of some members of the union.”

As a result, he has brought proceedings seeking orders including one preventing the defendant from swearing in a new president and an order setting aside last month’s election results.

He also seeks a declaration that at the elections held on 15th of July, 2018 by the IGBO Union Dublin for the positions of president and deputy-president were invalid.

The application came before Ms Justice Miriam O’Regan, who after declining to grant the plaintiff a temporary injunction preventing the swearing in of the new president, but was prepared to grant permission to serve short notice of the proceedings on the defendant.

The judge made the matter returnable to a date next week.

THIS ARTICLE WAS PUBLISHED HERE ON AUGUST 16, 2018

Get To Know Lucy Azubuike, On A Mission To Photograph The Identity Of One Million Trees

Lucy Azubuike image courtesy of the State Journal

BY HANNAH BROWN
THE STATE JOURNAL

Lucy Azubuike is on a mission to photograph a million trees — a million is called “agûkata agba awahûü,” in the Igbo language. It loosely translates to “too many to count.”

Azubuike, a native of Nigeria, has been serving as resident artist at Josephine Sculpture Park this summer. She started July 7 and will wrap up at the end of this month.

Her photographs aren’t just pictures of trees. She finds the trees’ true identities.

“I am a visual artist, but I let the tree be the ultimate artist,” Azubuike said.

She takes notice of details within the bark, knots, lichens and shapes of the limbs. She may see a human face, figure or animal.

She seeks to find a common ground between humans and the trees.

“Nature is you,” Azubuike said. “I hope to go to as many parks in America, and beyond, and give the trees an identity.”

Azubuike obtained her bachelor’s degree from the University of Nigeria. In 2012, she came to the U.S. to attend Savannah College of Art and Design in Atlanta. She graduated in 2015 with a master’s degree in sculpture and moved to Indianapolis.

Azubuike hopes to make Kentucky her full-time home.

State Journal: Why did you decide to do the residency at Josephine Sculpture Park?

Azubuike: Josephine Sculpture Park’s mission is exactly what I’m looking for — connecting people with the land and nature.

I get to explore and create something to allow people to connect with nature and themselves. The images in the trees reveal themselves to you. Every time I come out, I see something. There are surprises everywhere in the trees.

My time here at the park is meditative. I will install a sanctuary, an initiation ground for the sculptures made by trees in the park. It will house few pictures of some images I found in the park. Then there will be a map that visitors can use to go and try to find the images on the trees.

SJ: Describe your project “One Million Trees.”

Azubuike: Most people, when I say I’m going to identify images in one million, they say “how can you do that?”

I’m talking about one million trees around the world. It’s possible. I will have to be consistent. It’s a symbol of “agûkata agba awahûü” in my language of Igbo, which means you are counting too much. There are too many to count. It means it’s almost uncountable.

I have photographed so many trees, I already can’t count them all.

SJ: Have you held any classes at JSP?

Azubuike: I had one nature photography workshop. I taught participants how to frame pictures, take them and find them. Just pretty much what I do for myself. It was awesome.

SJ: How does it make you feel to be able to share your passion for photographing trees with others?

Azubuike: It’s an amazing feeling. The joy does everything for me. To see people feel the same as me, that’s something I want to continue to do. You see the light in their eyes and how they smile and live. These trees are promoting conversation and making people curious.

SJ: How do you like Kentucky?

Azubuike: It feels like home. I hope someone will give me a piece of land to live on — someone will say, “Take this 10 acres,” so I can keep doing my project. I know we have farms and horse ranches, and I hope to have Lucy’s tree ranch. The world is my ranch. I would like to live here full time. I like it here.

People have a misconception of Africa. They think Africa is a jungle. I’ve never seen anywhere like Kentucky. Kentucky is the jungle. I grew up in a metropolitan area in Nigeria. I saw trees only when we visited family in the village. Unfortunately, we visited only once each year. I love the village.

Before I came here, they said this is an industrial nation and the trees were dead, but no.

All these preconceived notions. Just like with trees. You see the tree, you might just think it’s just a tree, but look at the images I found.

Until you see it with your pure eyes and clean mind, that’s when you see something else and something valuable. It will add something to your life.

SJ: What do you hope people walk away with after seeing your photographs?

Azubuike: Open-mindedness. People should appreciate beyond what you expect. I hate preconceived notions. Yes, it could be what it is, but it could be more.

What I want most is that connection — for people to see themselves in the trees. When you see yourself in something, then you respect and appreciate it. It’s the same. The sky above us is the same. The unity and the nature.

Wherever you see a tree, that is what you are and who you are. Everywhere is your home. Nature is you. Nigeria has dramatic trees, so do other countries. Some of my tree images were from countries like Istanbul, France, South Africa and others. One cannot tell which is from a particular country until I point it out. This is to show people that it’s not about a particular location, it’s around the world. The sky above us is the same.

I share my culture through the trees and I hope to get the same wherever I go. I want people to reflect what evokes them.

This Nigerian Doctor Might Just Prevent The Next Deadly Pandemic

As leader of the Nigeria Centre for Disease Control, Chikwe Ihekweazu works to protect the nation — and the world — from devastating outbreaks.


Chikwe Ihekweazu aims to build a public-health agency that will stand the test of time.Credit: Andrew Esiebo via Nature


Chikwe Ihekweazu tried to steel himself as he surveyed people writhing in pain beneath ramshackle tents in the deserts of northern Nigeria. A deadly epidemic of meningitis had swept through the region in 2017, debilitating so many people that clinics had run out of space.

The tragic scene laid bare the challenges ahead for Ihekweazu, who had just been appointed director of the nation’s first agency tasked with tracking and responding to outbreaks, the Nigeria Centre for Disease Control (NCDC). Local health workers either didn’t know to report cases, or reporting lagged behind because they lacked electricity to charge mobile phones and laptops. Samples of spinal fluid spoilt before they reached the NCDC’s microbiology laboratory in Abuja, which made it impossible to confirm diagnoses — a requirement for unlocking access to international stockpiles of vaccines. As the agency struggled to count cases, the outbreak wore on, eventually infecting more than 14,000 people and killing almost 1,200. “That’s when it became clear how quickly things can fail,” says Ihekweazu.

Nigeria is Africa’s most populous nation and its biggest economy, but it is also the world’s poorest, as measured by the number of people living in extreme poverty. It is routinely battered by infectious diseases: meningitis, measles, cholera and newly emerging threats that plague communities and raise alarms around the world.

Ever since the Ebola crisis of 2014–16 — from which Nigeria was largely spared — global-health leaders have been fretting about the possibility of an epidemic exploding in Lagos and spreading to London, New York, Mumbai or Beijing. Many argue that the best hope of mitigating such a catastrophe will come from the capacity of African nations to catch outbreaks early and stem their spread. Ihekweazu had written about this necessity long before it was in vogue — but he never imagined leading the effort himself.

Yet just two years after his appointment, he has more than doubled the size of the NCDC staff, set up a network of molecular-biology labs across the country and become the steward of multimillion-dollar grants intended to diffuse the threat that an epidemic in Nigeria poses for the rest of the world. On his watch, the nascent agency has battled about a dozen outbreaks, which have infected more than 70,000 people (see ‘Keeping tabs’). “We are building the ship while we are sailing,” Ihekweazu says. Now he has another two years to transform the NCDC into an organization that will operate successfully long after he’s gone.

Many have faith that he can do so, because he’s proved to be an agile leader in a fragile part of the world. Furthermore, they hope that his strategies in Nigeria might be repeated elsewhere on the African continent, such as in the Democratic Republic of the Congo. “Chikwe is showing that Africa can do what is needed, when it’s needed,” says David Heymann, an epidemiologist at the London School of Hygiene and Tropical Medicine. “He is leading the way in how things can be done.”
Shared vision

Ihekweazu was born in Igboland in southeastern Nigeria in 1971, a year after the region had lost the Biafran War for independence from the rest of the country. The war left the Igbo people malnourished, traumatized and persecuted. But inhabitants of the communal university town of Nsukka hoped for a better future. Ihekweazu’s father was a Nigerian doctor there, and his mother, a German, was a professor at the university. “They had moved there to rebuild the community,” Ihekweazu says. “Our home was a melting pot for all sorts — her students, his patients — we had a sense that whatever we have, we share.”

After completing medical school at the University of Nigeria in Nsukka, Ihekweazu moved to Germany, where he received a master’s degree in public health and then worked in the national health system. In 2002, he became an epidemiologist at what is now Public Health England in Bristol, UK. One of his mentors, James Stuart, a Bristol-based consultant for the World Health Organization (WHO), remembers Ihekweazu as highly skilled but utterly unassuming. When Ihekweazu was assigned to investigate an outbreak of Escherichia coli in Cornwall, UK, for example, the local authorities resisted handing over the case. “Chikwe managed to listen to everyone, respected their contributions and made them feel as if they were leading it,” Stuart recalls. Together, the team found that cattle faeces had contaminated a stream, and that children playing near the water were getting infected (C. Ihekweazu et al. Euro Surveill. 11, 613; 2006).

Others have noticed his knack for gliding between cultures and pushing people to cooperate for the common good. Ihekweazu attributes these skills to his upbringing and the frequent experience of being mistrusted initially for being Nigerian. “I have grown up with these tensions,” he says. “With more or less time, most people eventually get over it.”

Ihekweazu had always imagined that he’d return to Nigeria one day, but the idea caught fire when he attended a TED conference in Tanzania in 2007, where African speakers talked about how fulfilled they felt to be improving their home countries. One speaker, Kenyan lawyer Ory Okolloh, lamented the way in which the West frames Africa as a place to be pitied, rather than as one that is rich with people who succeed despite the odds. After the presentations, Ihekweazu said to his closest friend, Ike Anya, a fellow Nigerian public-health specialist in the United Kingdom, “It is time to go home.”

Their first move was to launch a blog commenting on health issues in Nigeria. During the 2009–10 H1N1 influenza pandemic, Ihekweazu criticized the country for being unprepared. “Nigeria needs a central, well-resourced centre for infectious disease prevention and control,” he wrote in 2010, “or one day we will pay the price the hard way.” Out of the blue, he says, Nigeria’s health minister wrote to him to say that he was in London and wanted to meet. They talked at a coffee shop about fighting flu.

In 2011, Ihekweazu and his family moved to South Africa, where he became co-director of the national tuberculosis centre. He and Anya also launched EpiAfric, a health-care company that consults for organizations across Africa. When it came to their home country, however, working within a government that had long disappointed them was furthest from their minds. Anya says, “We had seen how the Nigerian bureaucracy would eat up and spit out the best intentions.”

But one July evening in 2016, Ihekweazu got a call from an official in Nigeria, telling him that in the morning, Nigerian President Muhammadu Buhari would appoint him head of the fledgling NCDC. He hadn’t applied for the job, nor did he particularly want it. By the next day, his inbox was overflowing with congratulatory messages. He switched off his phone and walked through the cool, damp streets of Durban, South Africa, pondering the long list of problems troubling Nigeria: poverty, conflict, corruption, dirty water, population growth. He realized that it would be hypocritical to have complained about the government’s approach and then reject an opportunity to fix it. He was going home.

Step change

Ihekweazu would be moving from nations with established public institutions to a country where government agencies were comparatively young. After Nigeria won independence from Britain in 1960, it was left with vanishingly few doctors, scientists or leaders to serve the massive population. Academics who might have built up national health agencies in the decades following independence left Nigeria in waves as the nation was shaken by civil war, nine military coups and erupting tensions among some 200 different ethnic groups. And, unlike more-authoritarian nations that have advanced unified health systems, such as Rwanda and Ethiopia, Nigeria’s 36 states operate rather autonomously. “We have had to build a country within boundaries drawn by Europe, among people who didn’t live together,” Ihekweazu says. “So it’s always a struggle.”

Without strong national institutions, decades of outside aid and research projects have failed to increase the average life expectancy of Nigerians beyond age 53. Piecemeal programmes that deliver HIV drugs or that analyse patterns of viral transmission can be helpful. But these projects do not build a nationwide system capable of figuring out why a community falls ill, helping people recover and preventing future crises. When Ebola ripped through Sierra Leone, Guinea and Liberia from 2014 to 2016, it showed that systemic failures pose a risk not only to those directly affected, but also to other countries. Mitigating that risk is costly: donors spent around US$3.3 billion to end the outbreak in West Africa. World health officials pointed out that it would have been much better if hard-hit countries had been able to stop it themselves early on.

Richard Garfield, an epidemiologist at the US Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia, says that revelation fuelled a drive to shore up global health-security, in part by creating national public-health institutes. This agenda has become “the next big thing after HIV”, says Garfield. By 2016, the US government was contributing both finances and expertise to the effort, as were the United Kingdom, the World Bank and the Bill & Melinda Gates Foundation in Seattle, Washington, among others. But the task is monumental. So-called ‘vertical’ approaches that target specific diseases, such as polio, can ignore problems that are outside the scope of the project. To address multiple underlying causes of illnesses, nations need a ‘horizontal’ system of labs, clinics and staff that stretch across a country. “Vertical programmes are simple,” says Garfield. “This is much broader,” he explains. It now falls to leaders such as Ihekweazu to turn donor dollars into institutions that last.

Free rein

On 13 November last year, President Buhari made the NCDC an independent agency, granting Ihekweazu authority over how he reports data, how he spends the budget and whom he hires. The move infused his team with energy, and a week later, people were still buzzing at the NCDC’s modest, concrete compound in Nigeria’s capital city of Abuja. In a single-room structure called the Incident Coordination Centre, wall-mounted monitors displayed updates on epidemics, sent in from satellite centres across the country. Next door, a young NCDC employee monitored a hotline and social media for outbreak indicators. They call the system Tatafo, using the Yoruba word for gossip.

Ihekweazu and his team were preparing for a spike in Lassa fever, a viral haemorrhagic disease that, like Ebola, can swiftly cause death through internal bleeding. Cases of Lassa fever typically surge in Nigeria between December and March, and it caused a record 184 deaths last year. During the peak of that outbreak in early 2018, Ihekweazu had travelled to a hard-hit hospital in Abakaliki in the southeastern state of Ebonyi. The hospital’s virology centre was almost barren, with hardly any electricity or treated water. The team there had run out of antiviral drugs and protective gear for health workers. And people were dying as they waited for the results of diagnostic tests that had to be conducted outside the state. Although the lab had a PCR machine that could be used to identify the disease, it sat broken on a shelf. A group of researchers from Japan had brought it as part of a research project, but when they left, no one knew how to use or maintain it.

To curb the number of deaths, Ihekweazu has spent the past year supplying hospitals in Ebonyi and other states, and organizing training sessions for staff so that they can detect and report Lassa fever rapidly. When he returned last November, a chief doctor and the head of the virology lab greeted him outside. Freshly installed solar panels glinted in the morning sun, and dust from construction hung in the air — workers were building a new ward for patients with Lassa fever and an incinerator for infectious material. Inside the lab was a new biohazard hood, where technicians could deactivate live viruses in blood samples. The broken PCR machine remained in another room, but it had been joined by two new ones given by the NCDC. Ihekweazu told the team that he had sent one of his staff to Japan to learn to repair and maintain such technology. “Across Nigeria, you’ll find millions of dollars’ worth of equipment not running for some small reason,” he said.

Walking around the grounds, the group discussed how to grapple with Lassa fever beyond the hospital gates. Ihekweazu asked them to help brainstorm studies that would reveal how people were catching the virus from its host, the African rodent Mastomys natalensis, so that this mode of transfer could be prevented. The chief doctor expressed his concern that infected people were arriving at the hospital too late to be saved by treatments. The NCDC had been running radio advertisements urging people to seek medical care rapidly. But the Ebonyi state epidemiologist said it wasn’t enough. They needed feet on the ground: community members who could spread the word and call him when they spotted someone who might be infected. Such volunteers needed petrol to get to remote towns, and credit on their mobile phones to make calls. “Amazing how something like airtime can stop a response,” Ihekweazu said, adding that the NCDC lacked funds for this but that he’d think of a solution.

Later that evening, Ihekweazu confessed that he remained anxious. “Lassa starts with a little trickle,” he said, “and then sometimes it goes boom.”
Cash flow

Money is always short. In 2018, the NCDC hobbled along on a government budget that was less than $4 million (for comparison, the US CDC’s budget last year was $11 billion). That comes to less than 0.02 cents per Nigerian per year (compared with the CDC’s $33 per American). Nigeria’s health system, as a whole, is one of the most poorly funded in the world. The government allotted just 0.6% of gross domestic product to health in 2015, compared with 4.4% in South Africa and around 8% in the United States and the United Kingdom.

“One of my biggest responsibilities is to fight for more money within the government budget,” Ihekweazu says. But it’s a difficult ask, because health investments rarely result in things that people see, such as airports or roads, he explains. “Politicians can’t say ‘look at the meningitis outbreak that didn’t happen’ and have it win them votes.”

So Ihekweazu is also appealing to Nigeria’s thriving private sector, explaining how a fast-moving outbreak of Ebola could bankrupt their companies. He says that businessman Aliko Dangote, the richest man in Africa, has expressed an interest in supporting the agency. “We are discussing something around laboratory networks, since his companies’ biggest strengths are in logistics and manufacturing,” Ihekweazu says.

More than anything, Ihekweazu struggles to afford the staff he requires. He’s managed to grow the agency from 90 people to 213. Nearly half of NCDC employees are under 30 years of age. That’s partly due to the low salaries he has to offer, but Ihekweazu loves their willingness to learn and their energy. Nanpring Dawn Williams, a microbiology graduate working one night in the Incident Coordination Centre, described how Ihekweazu recognized her skill at managing data. “Now he’s always asking what new papers I’ve read,” she says. “He expects me to publish a manuscript.” With a smirk, her colleague Anwar Abubakar says, “He knows we are single and no one expects us to come home at the end of the day.” But he adds that his boss pushes himself even harder, and drives his team by conveying the importance of their mission. “He tells us we are the future of the organization.”

Still, the agency has too few experienced epidemiologists and molecular biologists. To hire them, Ihekweazu must convince outstanding Nigerian scientists to work for much less than they would earn in the private sector or at aid organizations. Anthony Ahumibe, the laboratory adviser at the NCDC, explained how Ihekweazu poached him from a well-paid job at AFENET, a non-profit public-health organization funded by the US CDC. After they met in 2017, Ihekweazu called him at 10 p.m. every few weeks. “He said, ‘I cannot pay you as well, but depending on how hard you work, and how focused you are, there will be so many opportunities’,” Ahumibe recalls.

Ihekweazu’s dedication also attracts Nigerians who live abroad. “This is an experiment in brain gain,” explains Emmanuel Agogo, who had been a UK physician before joining the NCDC. “We are trying to create a system where none exists.” For this reason, Ihekweazu convinced the Bill & Melinda Gates Foundation to help fund salaries for management-training consultants, a feature typical of wealthy corporations. It might sound like a luxury in a country where clinics lack gloves, but Ihekweazu explains that it stems from decades of watching well-intentioned projects evaporate because donors invest in things, but not people.

Careful choices

When Ihekweazu is not travelling, he can be found in his office in Abuja, with his large frame hunched over a laptop or intercom, rubbing his forehead between his thumb and his forefinger. From there, he corresponds with donors and researchers in rich countries who wish to conduct projects and experiments in Nigeria. Each grant comes with requests that Ihekweazu navigates carefully. “We need the expertise and collaborations,” he says, “but we want a real partnership, not a master–servant relationship.”

His largest programme to oversee is a 5-year, $90-million global health-security project from the World Bank to strengthen Nigeria’s national surveillance system. And in January, two international consortia announced that they will collaborate with the NCDC to develop diagnostic tests and vaccines for Lassa fever. Dhamari Naidoo, a WHO technical officer based in Nigeria, says: “Researchers wanting to do clinical trials are now lining up to work with [Ihekweazu] because he pushes his people to deliver like you cannot believe.”

But Ihekweazu knows that the international focus on pandemic preparedness will eventually wane — as all fads do. So he is trying to ensure that the supply chains and lab networks he’s building to monitor pathogens will last. John Nkengasong, director of the Africa Centres for Disease Control and Prevention in Addis Ababa, hopes that the NCDC will soon have the power to help outbreak responses across West Africa. “We can’t ensure the safety and security of our continent while relying on someone else’s goodwill,” Nkengasong says.

Ihekweazu takes heart in seeing Africans such as WHO director-general Tedros Adhanom Ghebreyesus step onto the global stage. Sipping on a cheap beer during a quiet moment one night, Ihekweazu says he could imagine working at a multinational health agency when his appointment at the NCDC ends in 2020. “As Africans, we need to be stronger participants in the organizations leading the responses to challenges concentrated in our part of the world,” he says.

But the following evening, the bags under his eyes seem deeper as his phone blinks with texts about problems ranging from the major to the mundane. He pictures a future tucked away in a university lab. “Some days I feel we are at the beginning of something huge and exciting, and sometimes I feel like this is too hard a job. It’s 24 hours a day. The generators don’t work. A vehicle is stuck.” His lab adviser Ahumibe excuses himself from the table as if he cannot breathe without the oxygen of Ihekweazu’s optimism.

“‘Look after your health’ is the last thing I always say to him before I hang up,” says Anya, Ihekweazu’s close friend. And Sola Aruna, one of his public-health colleagues in Nigeria, says she worries that political events might prompt Ihekweazu’s premature replacement. “I am fearful since a very good thing has happened with him here,” she says. “Now the negative side is that people are sitting up, they see the NCDC in the news, and some people may think that what he’s doing is easy.”

Those who understand public health have been impressed by Ihekweazu’s progress in building the foundation of the agency, but demonstrating its power to Nigerians could take time. A perverse twist to bolstering surveillance is that problems look worse before they can get better. During Ihekweazu’s tenure, the NCDC has announced the worst outbreaks of Lassa fever, yellow fever and cholera in a decade, and detected the first cases of monkeypox in 40 years. But Ihekweazu knows that the only way to fight these diseases is to bring them to the surface. “I can give up and say this problem is bigger than me,” Ihekweazu says. “Or I can buckle down and push.”

Akwaeke Emezi: ‘I’d Read Everything – Even The Cereal Box’

Akwaeke Emezi image via The Guardian, London

BY ARIFA AKBAR

Akwaeke Emezi, 31, is a writer and video artist of Nigerian and Malaysian heritage and a “nonbinary trans and plural person”. Nigerian-born and raised, they currently live in Brooklyn. In 2017 Emezi won the Commonwealth short story prize (for Africa region) for Who Is Like God? Their highly acclaimed first novel, Freshwater, is a coming-of-age story that follows Ada from a troubled childhood in Nigeria to an American university where a traumatic event takes place. The book is about sexual, spiritual and emotional awakening and the negotiating of many inner voices inside a multiple self. The New York Times has hailed it a “remarkable and daring debut novel” and the New Yorker as an “indigenous fairytale”. Emezi’s children’s book, Pet, is to be published in 2019, and their second adult novel, The Death of Vivek Oji, is also due for publication.

Your central character, Ada, is a Nigerian student in America who is inhabited by ogbanje, which I understand to be spirits in Igbo…

Ogbanje are children who die over and over again. They are considered to be tricksters, torturing their parents who hope they will stay alive. Ada is a spirit child, or ogbanje. She is not possessed by spirits; people think in binaries a lot, so that one thing has to be possessed by another. But with ogbanje, these things are collapsed.

So the voices are different sides of herself?

Yes, the way I describe Ada is as a singular collective and plural individual. Ada is described as a “girl” but is not, actually. “She” has gender-affirming surgery and it is not said but she is trans.

Do you believe in the spiritual world?

I think multiple realities exist. Most colonised countries had their cosmology, their ontology, their metaphysics colonised too. They’ve been told that what was there before wasn’t real. My dad’s a pretty conservative Christian, but he’ll still get a pastor to come to the hospital [where he works as a doctor] because someone’s been working black magic. I say to him: “If you don’t believe in it, why is the pastor there?” He says: “You don’t need to believe in something for it to be real.”

Jesus features in this book and he is brilliantly satirised, though he is not condemned. Was this meant to be a critique of Christianity?

Ada is reassessing her relationship to Christianity. Some readers have flagged this up as blasphemous... but Ada is not picking one or the other [side] but dealing with both at the same time; her relationship with Christianity is in flux. I’ve looked at my life through the lens of Christianity [Emezi was raised as a Catholic]. Then I came to America, had therapy, and looked at my life through the lens of western mental health. None of it helped me. I had trouble staying alive. When I began to look at my life through the lens of Igbo ontology and craft it as a story, then, for the first time, everything clicked into place.

The book deals with self-harm, rape, suicide and psychic trauma, but none of these things are named as such. Why?

There’s a very deliberate choice to narrate the story from a different centre. There’s a mainstream centre that would have let Ada narrate more of the book, that would have framed things in language that people are comfortable with. My lens is different, and it [the book] has a non-human centre.

Ada’s mother is Malaysian, her father is Nigerian, as are yours. Like you, she goes to America to study. Is it right to say that the book is partly based on personal experience?

It’s an autobiographical novel – a breath away from being a memoir. There are chapters in there that are my journal entries which I copied and pasted. There are a couple of things about writing it this way: first, the things that people think are fictionalised are not fictionalised. Second, I wanted to make clear it was autobiography, otherwise it would be considered to be very fantastical. I wanted readers to be sure that it was not magical realism or speculative fiction. It’s what has actually happened! I’m using fiction as a filter for it.

Chimamanda Ngozi Adichie has spoken of “the danger of the single story” and relates it to her own Nigerian childhood experience of reading stories about white-skinned, blue-eyed characters. What did you grow up reading in Nigeria?

In school I read a lot by African writers, but at home my parents’ book collections were way more western. My dad went to medical school in Russia and met my mom in London while she was at nursing school. The books ranged from Dostoevsky and Tolstoy to all the British children’s books: Enid Blyton, CS Lewis, JK Rowling. I read all of them.

What’s the last really great book you read?

I recently reread Helen Oyeyemi’s The Icarus Girl. I liked reading it the first time, but I read it after Freshwater was published and I cried because there were so many parallels I hadn’t been aware of. It’s the first book she wrote and it has a different quality from the rest: this one is big and sprawling and scary. I’d forgotten how scary it was.

Which genres do you particularly enjoy reading? Are there any you avoid?

I’m still the kid trying to read about fantasy worlds to get away from this one. It’s not like I have never read contemporary literary fiction, but I would much prefer to read speculative fiction. One of my absolutely favourite writers is NK Jemisin, and the Malaysian writer Zen Cho is amazing.

Who is your favourite literary hero or heroine? Antihero or villain?

I’m not sure about hero or heroine, but there’s a villain in Octavia Butler’s Patternist series called Doro. I read the first book and hated him so much that it took me years to read the rest of the series. It was a visceral feeling. He is a rapist and controls people’s minds.

What kind of reader were you as a child?

Voracious. I read literally everything I could get my hands on – the shampoo bottle, the cereal box. My mom didn’t let us have books at the table or we’d all have read. We didn’t always have electricity, so I read by candlelight. I read really fast too. My parents realised I’d run out of things to read and were like: “We need to buy you way more books.”

Which book or author do you always return to?

Terry Pratchett. He wrote 40-something books based in one invented universe.

Scientists Advance Natural Cures For Cancers





Scientists have advanced in the search for natural cures for cancers.

Latest findings showed onions, leeks, and garlic slash the chance of getting deadly bowel tumour; diet rich in whole grains, bran, and cereal fibre reduces risk of liver cancer by 40 per cent; and how chronic stress boosts malignant cell growth.

A study published in the Asia Pacific Journal of Clinical Oncology found that Allium vegetables – which also include garlic, leeks, chives and shallots – dramatically cut the risk of bowel cancer.

The study of more than 1,600 men and women found those with the biggest intake were 79 per cent less likely to develop bowel cancer than those with the least.

Bioactive compounds in allium vegetables have previously been shown to protect against breast and prostate cancer.

Senior author of the latest study, Dr. Zhi Li, of the First Hospital of China Medical University in Shenyang, said: “The greater the amount of allium vegetables, the better the protection.”

The researchers found eating at least 35lb a year could reduce bowel cancer risk. This would be around one-and-a-half ounces a day – equivalent to an onion.

The study, published in the Asia Pacific Journal of Clinical Oncology, compared 833 bowel cancer patients with the same number of healthy controls, using a food frequency questionnaire.

Li pointed out that cooking method had an effect. For example, boiling onions reduced useful chemicals, while slicing and crushing fresh garlic was beneficial.

Earlier studies showed extracts from onion, garlic, lime, olive oil, hog plum, chieftaincy leaf, and asthma herb provided novel cure for ear, nose and throat infections.

The researchers showed the efficacy of naturopathic herbal extract (consisting of Allium sativum (garlic), Verbascum thapsus (mullein flowers), Calendula flores (marigolds), and Hypericum peroforatum (St. John’s wort) in olive oil in the management of ear pain associated with acute otitis media (AOM).

The study published in the journal JAMA Pediatrics and Archives of Pediatrics & Adolescent Medicine is titled “Efficacy of Naturopathic Extracts in the Management of Ear Pain Associated With Acute Otitis Media.”

The researchers evaluated the efficacy and tolerance of Otikon Otic Solution (Healthy-On Ltd, Petach-Tikva, Israel), a naturopathic herbal extract (containing Allium sativum, Verbascum thapsus, Calendula flores, and Hypericum perforatum in olive oil), compared with Anaesthetic (Vitamed Pharmaceutical Limited, Benyamina, Israel) ear drops (containing ametocaine and phenazone in glycerin) in the management of ear pain associated with acute otitis media (AOM).

Also, researchers have identified and validated garlic as one of the local spices and food items that could be effectively used to control and manage hypertension. Others are: beetroot, Zobo and banana.

Yet another study validated garlic and onions for the treatment of drug resistant malaria and typhoid fever.

A herbal preparation made predominantly with garlic, ginger, onions, scent leaf, lemon grass, unripe pawpaw, lime/lemon, African pepper (Uda in Igbo), clove, Gongronema latifolium (Utazi in Ibo, arokeke in Yoruba) and West African Black pepper (Uziza in Igbo) has been effectively used to stop malaria and typhoid.

Also, naturopaths recommend eating onions, leeks and artichokes if you are stressed and struggling to sleep. For scientists have discovered that the popular vegetables could help humans to relax – allowing them a better night’s sleep.

Also, another new study found that a diet high in whole grain, bran and cereal fibre lowers the risk of liver cancer.

The study was published in JAMA Oncology.

But the United States (U.S.) scientists found that an increased intake of fruit or vegetable fiber did not have an effect.

Those who ate the most whole grains in their diet had a 37 percent lower risk than those whose diets were sparse of the healthy grains.

A high bran diet also reduced the risk by 30 percent while germ reduced it by 11 percent.

Added bran reduced the risk by 31 percent but added germ actually increased the risk by 22 percent.

They added whole grains; bran and cereal fiber reduces insulin resistance, hyperinsulinemia, and inflammation – all known hallmarks of cancer.

Associate Epidemiologist at Brigham & Women’s Hospital and Assistant Professor at Harvard Medical School, Dr. Xuehong Zhang, said: “Increased intake of whole grains and possibly cereal fiber and bran could be associated with reduced risk of HCC among adults in the United States.

“Whole grains are a major source of dietary fiber and consist of bran, germ, and endosperm, compared with refined grains that contain only the endosperm.

“The whole grains are good sources of dietary fiber, vitamins, minerals, phytonutrients, and other numerous nutrients, which are removed during the refining process.”

He added: “Consumption of whole grains and dietary fiber, especially cereal fiber, has been associated with lower risk of obesity, type 2 diabetes, and nonalcoholic fatty liver disease, which are known predisposing factors for HCC.

“In addition to improving insulin sensitivity and metabolic regulation and decreasing systemic inflammation, intake of whole grains and dietary fiber may improve gut integrity and alter gut microbiota composition, thereby leading to increased production of microbiota-related metabolites, including short-chain fatty acids, particularly butyrate.

“Gut integrity, the composition of gut microbiota, and metabolites may play an important role in the development of liver diseases, including HCC.”

So the study followed 77,241 women and 48,214 men with a mean age of 63.4 taking part in the Nurses’ Health Study and the Health Professionals Follow-up Study.

Their intake of whole grains, their subcomponents (bran and germ), and dietary fiber (cereal, fruit, and vegetable) were assessed every four years over an average follow-up of 24.2 years.

Those in the highest tertiles of whole grain and dietary fiber intake were slightly older, had lower Body Mass Index (BMI), exercised more, drank less, did not smoke, more likely to take aspirin and had higher intake of fruits, vegetables, total folate, multivitamin, and dietary vitamin D, but less fat compared with those in the lowest tertiles.

BMI is a measure of weight in kilogrammes/height in metres squared (Wkg/Hm2).

A total of 141 patients were diagnosed with HCC.

Zhang said: “Interestingly, compared with fruit or vegetable fiber, cereal fiber has been shown in our study and other cohort studies to be more consistently associated with lower risk of total mortality, cardiovascular disease, type 2 diabetes, and colorectal cancer.

“However, our results on the association of cereal fiber with HCC risk could have been due to chance.

“Alternatively, a potential explanation is that fruits and vegetables, particularly fruit juice, contain sugar or added sugar such as fructose and sucrose, which may lead to hepatic damage and nonalcoholic fatty liver disease, thereby masking the potential benefit of fruit- or vegetable-fiber intake.

“Overall, the exact reasons for such a difference remain unknown and require further investigation.”

He added while more research was needed he concluded: “If our findings are confirmed, increasing whole grain consumption may serve as a possible strategy for prevention of primary HCC.”

Meanwhile, having conducted a new study in mice, researchers now have a much better understanding of how chronic (long-term, sustained) stress can accelerate the growth of cancer stem cells. They may also have found a way to prevent stress from doing its damage.

Chronic stress, which a person has consistently over a long period of time, affects mental and emotional well being as well as physical health.

Studies have tied chronic stress to accelerated cognitive impairment, a higher risk of heart problems, and problems with gut health.

Previous research also suggests that exposure to stress could speed up the growth of cancer through its impact on gene activity.

Now, researchers from the Dalian Medical University in China — in collaboration with colleagues from across the world — have located a key mechanism, which chronic stress triggers that fuel the growth of cancer stem cells that tumors originate from.

More specifically, the researchers have studied this mechanism in mouse models of breast cancer.

Their findings — which they report in The Journal of Clinical Investigation — point the finger at the hormone epinephrine, but they also suggest a strategy to counteract the effects of stress mechanisms on cancer cells.

“You can kill all the cells you want in a tumor,” notes co-author Keith Kelley, from the University of Illinois at Chicago, “but if the stem cells, or mother cells, are not killed, then the tumor is going to grow and metastasize.”

He added: “This is one of the first studies to link chronic stress specifically with the growth of breast cancer stem cells.”

To see how stress would impact cancer cell growth in the rodents, the researchers put all the mice in small, restrictive enclosures for a week. Then, they split the mice into two groups.

They put one group into large, comfortable enclosures to discontinue the stress; these mice acted as the control group. The other group stayed in the small enclosures for another 30 days; these mice acted as the experimental group.

Cutting-edge research may bring us a better understanding about the spread of breast cancer.

Following their initial investigation, the scientists saw not only that the stressed mice exhibited changes in behavior that were indicative of depression and anxiety, but also that they had larger cancer tumors than their peers in the control group.

Also, these tumors were growing at a faster rate, and on the whole, the stressed mice also had a greater number of cancer stem cells than the other mice.

Still, at this point, it remained unclear exactly how stress contributed to the progression of cancer.

According to principal investigator Quentin Liu, from the Institute of Cancer Stem Cell at Dalian Medical University, “The direct signaling network between stress pathways and a cancer-propagating system remains almost completely unknown.”

He added: “A better understanding of the biochemistry that causes stress to increase the growth of cancer cells could lead us toward targeted drug interventions, one of which we discovered in this work.”

When they looked into how various physiological factors changed in the mice that had experienced chronic stress, the researchers closed in on a hormone called epinephrine.

The stressed mice had much higher levels of this hormone than the mice in the control group.

Also, in mice from the experimental group that had received a drug that blocked ADRB2 — which is an epinephrine receptor — cancer tumors were smaller and the numbers of cancer stem cells were also lower.

Kelley said: “When most people think of stress, they think it is cortisol that is suppressing the immune system. However, the amazing thing is cortisol was actually lower after a month of stress.”

How does epinephrine help cancer stem cells thrive? The authors explain that when this hormone binds to ADRB2, the interaction boosts levels of lactate dehydrogenase, an enzyme that normally gives muscles an “injection” of energy in a danger situation. This allows the person to either fight the threat or run away from it.

A byproduct of this energy boost is the production of an organic compound called lactate. In the case of people with cancer, the harmful cells actually feed on this compound; it allows them to acquire more energy.

This means that if a person has chronic stress, they will have too much lactate dehydrogenase in their system. This, in turn, will activate genes related to cancer growth and allow cancer cells to thrive.

“These data provide a novel pathway that explains how elevated epinephrine caused by chronic stress promotes breast cancer progression by acting directly on cancer stem cells.”

Is vitamin C the answer? Next, the researchers validated their results by studying blood epinephrine levels in 83 people with breast cancer.

Sure enough, they found that people with high blood levels of epinephrine also had excess lactate dehydrogenase in cancer tumors — which the researchers had, access to through breast cancer biopsy samples.

Also, people who had higher levels of the stress hormone were likelier to have poorer outcomes following treatment when compared with people with lower epinephrine levels.

Next, the scientists tried to see whether or not they could identify a strategy to block epinephrine’s ill effects on the system.

In laboratory tests on breast cancer cell lines, they analyzed the effects of a few Food and Drug Administration (FDA)-approved drugs on lactate dehydrogenase production.

The most promising substance that the investigators settled on was actually vitamin C, which blocked actate dehydrogenase production in laboratory experiments.

When the investigators tested this approach in mouse models, they obtained the same results: Stressed mice they’d injected with vitamin C experienced tumor shrinkage.

Liu concluded: “Taken together, these findings show that vitamin C might be a novel and effective therapeutic agent for targeting cancer in patients undergoing chronic stress.”


SOURCE: THE GUARDIAN